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[摘要]
摘要:目的:分析接受IVF-ET治疗蒙古族与汉族女性主要临床及实验室指标的差异。方法:回顾性分析2016年1月至2019年12月在内蒙古医科大学附属医院生殖医学中心接受IVF助孕新鲜胚胎移植2597个周期与冻融胚胎移植2611个周期患者临床资料,根据女性民族不同分为新鲜胚胎移植蒙古族组302个周期、新鲜胚胎移植汉族组2295个周期;冻融胚胎移植蒙古族组320个周期、冻融胚胎移植汉族组2291个周期,分别统计新鲜胚胎移植与冻融胚胎移植中民族差异对患者妊娠结局的影响。 结果:新鲜胚胎移植中,蒙古族就诊患者原发不孕比例、优质胚胎率高于汉族患者,蒙古族患者和汉族患者在活产率、临床妊娠率、囊胚率、胚胎种植率、卵裂率和受精率上比较无统计学差异(p>0.05);冻融胚胎移植中蒙古族患者与汉族患者在活产率、临床妊娠率、胚胎种植率上无显著性差异(p>0.05)。结论:蒙古族和汉族女性患者接受辅助生殖助孕后,胚胎移植后妊娠结局无显著性差异,民族差异不影响妊娠结局。
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[Abstract]
【Abstract】Objective To investigate the differences in main clinical and laboratory parameters between Mongolian and Han women undergoing IVF-ET. Methods A retrospective analysis was performed on the clinical data of 2597 cycles of fresh embryo transfer and 2611 cycles of frozen thawed embryo transfer (FET) from January 2016 to December 2019 in the Reproductive Medicine Center of The Affiliated Hospital of Inner Mongolia Medical University.?In the fresh embryo transfer group, there were 302 cycles in Mongolian patients and 2295 cycles in Han patients.?In the frozen-thawed embryo transfer group, 320 cycles were performed in Mongolian patients and 2291 cycles in Han patients. The effects of ethnic differences on pregnancy outcomes in the fresh embryo transfer group and the freezing-thawing embryo transfer group were analyzed. Results Compared with Han patients, Mongolian patients had higher age and primary infertility rate, and higher high-quality embryos rate. The differences were statistically significant (p<0.05).?There were no significant differences in fertilization rate, cleavage rate, embryo implantation rate, blastocyst rate, clinical pregnancy rate and live birth rate between Mongolian and Han patients (p> 0.05).?In the Frozen-thawed embryo transfer group, the ages of Mongolian patients were significantly higher than those of Han patients (p> 0.05), but there were no significant differences in clinical pregnancy rate, embryo implantation rate and live birth rate (p> 0.05).?Conclusion After Mongolian and Han female patients received assisted reproduction for pregnancy, there was no significant difference in the pregnancy outcome after embryo transfer, and the ethnic differences did not affect the pregnancy outcome.
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[基金项目]
内蒙古医科大学附属医院成果转化项目(2022NYFYCGZH001);内蒙古自治区科技计划项目(2021GG0030);内蒙古自治区自然科学基金项目(2022MS03002);内蒙古自治区教育科学规划项目(NGJGH2022021)