[关键词]
[摘要]
目的: 探讨持续气道正压通气( continuous positive airway pressure，CPAP) 治疗对阻塞性睡眠呼吸暂
停低通气综合征(Obstructive sleep apnea hypopnea syndrome，OSAHS) 合并高血压病人的治疗效果。方法: 选取
2016－01～ 2018－02 期间就诊于内蒙古医科大学附属医院保健中心及心血管内科门诊且经多导睡眠监测确诊的
OSAHS 合并高血压的病人32 例为研究对象，在维持原有降压药物治疗的基础上，32 例病人予CPAP 治疗;分别
记录治疗前、后多导睡眠图和24 h 动态血压的监测参数，观察变化情况。结果: CPAP 治疗后呼吸暂停低通气指
数(sleep apnea hypopnea index，AHI)明显下降，最低血氧饱和度(minimal SaO2
，mSaO2
) 明显升高，差异具有统计
学意义(P＜0．05)。治疗后除了清晨血压，其余血压指标均较治疗前改善，并以24 h 平均收缩压、白天平均收缩
压改善显著占优。结论: CPAP 治疗能显著改善OSAHS 病人睡眠质量，同时能降低OSAHS 病人的血压。
[Key word]
[Abstract]
Objective: To investigate the treatment effect of continuous positive airway pressure
(CPAP) in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) complicated with hypertension．
Methods:Thirty － two patients with OSAHS complicated with hypertension diagnosed by
polysomnography at the Health Center and Cardiovascular Clinic of the Affiliated Hospital of Inner
Mongolia Medical University from January 2016 to February 2018 were selected as study subjects．On
the basis of antihypertensive drug therapy，32 patients were treated with CPAP; the parameters of
polysomnography (PSG) and 24h ambulatory blood pressure before and after treatment were recorded，
and observed the difference． Ｒesults:After treatment with CPAP，AHI decreased significantly and
mSaO2 increased significantly． The difference was statistically significant(P＜0．05)．After the treatment，
except for the early morning blood pressure，the remaining blood pressure indexes were improved compared
with those before treatment，and the 24 hMSP and dMSP improved significantly． Conclusion:
CPAP treatment can significantly improve the sleep quality and reduce the blood pressure of OSAHS
patients．
[中图分类号]
Ｒ562
[基金项目]
收稿日期: 2018－06－20;修回日期: 2018－08－11
基金项目: 内蒙古自治区自然科学基金面上项目(2017MS08113)
作者简介: 包丽丽(1991－)，女，蒙古族，内蒙古医科大学2015 级在读硕士研究生。
通讯作者: 贾海玉，主任医师，硕士研究生导师，E－mail:nmjiahaiyu@ qq． com 内蒙古医科大学附属医院保A 病区，
010050
