[关键词]
[摘要]
目的: 研究急性ST 段抬高型心肌梗死( STEMI) 和急性非ST 段抬高型心肌梗死( NSTEMI) 病人以及
Killip 分级、梗塞范围不同的AMI 病人血浆脑钠肽前体( NT－proBNP) 的变化及其临床意义。方法: 对300 例AMI
病人及正常对照组80 例进行NT－proBNP 的测定。结果: ( 1) AMI 组从KillipⅠ级到Ⅳ级血浆NT－proBNP 明显增
高，差异具有极显著统计学意义( P＜0．001) ; ( 2) STEMI 组和NSTEMI 组比较，NT－proBNP 差异具有极显著统计
学意义( P＜0．001) ; ( 3) STEMI 不同部位相比较，NT－proBNP 差异具有极显著统计学意义( P＜0．001) 。结论: 血浆
NT－proBNP 测定值的增高可反映心梗的严重程度和范围。
[Key word]
[Abstract]
Objective: To study the changes and clinical significance of plasma N－terminal probrainnatriuretic
peptide( NT－proBNP) between acute ST segment elevation myocardial infarction( STEMI)
and acute non ST segment elevation myocardial infarction( NSTEMI) patients．Besides， the changes
of NT－proBNP are in the Killip classification and different infarct scope of AMI patients．Methods: To
determine the NT－proBNP in 300 cases of AMI patients and 80 cases of normal control group．Results:
( 1) In the AMI group from Killip levelⅠ to Ⅳ， the plasma NT－proBNP increased obviously， the differences
have very significant statistical significance ( P ＜ 0．001) ; ( 2) Compared STEMI and NSTEMI
group，NT－proBNP difference has a significant statistical significance( P＜0．001) ; ( 3) Compared different
parts of STEMI，NT－proBNP difference has a significant statistical significance( P＜0．001) ．Conclusion:
The increased plasma NT－proBNP can reflect the severity and scope of AMI．
[中图分类号]
R541．6
[基金项目]
收稿日期: 2016－11－18; 修回日期: 2017－02－16
基金项目: 内蒙古医科大学附属医院科研立项( NYFY YB2014023)
作者简介: 李爱英( 1971－) ，女，内蒙古医科大学附属医院心内科主任医师，医学硕士。
