目的: 对宫颈癌组织、放疗后宫颈癌组织的磁共振影像学表现及表观扩散系数( Apparent Diffusion
Coefficient，ADC) 值进行分析，探讨T2WI( T2 －Weighted Imaging) 抑脂序列和磁共振扩散加权成像( Diffusion
Weighted Imaging，DWI) 技术在诊断宫颈癌及评价放疗后效果中的应用价值。方法: 选取2014－01 ～ 2015－06 就
诊于内蒙古医科大学附属医院经病理证实为宫颈癌的病人50 例，50 例宫颈癌病人进行磁共振矢状位T2WI 抑
脂序列扫描及横断面DWI 序列扫描( b = 1000s /mm² ) ，观察宫颈癌及宫颈癌放疗后的影像学表现，并测量相应的
ADC 值，比较宫颈癌放疗前后ADC 值的差异。结果: 48 例宫颈癌病人在矢状位T2WI 抑脂序列中可显示病变对
子宫肌层、浆膜层、阴道都有不同程度的侵犯，仅有2 例宫颈癌病人在矢状位T2WI 抑脂序列无明显异常。在
DWI 序列上50 例宫颈癌病人呈不同程度的高信号。放疗后，24 例病人恢复正常或出现炎性反应，放疗后病变
区ADC 值较放疗前升高，二者比值具有统计学差异; 20 例病人病变部分残留，6 例病人出现放疗后复发，两者
ADC 值较放疗前均无明显统计学差异，但与放疗后恢复正常或炎性反应组ADC 值比较有明显统计学差异。结
论: T2WI 抑脂序列和DWI 技术相结合是诊断宫颈癌及对宫颈癌病人放疗后效果评价较为有效、实用的方法。

Objective: To analyze the magnetic resonance imaging findings and apparent diffusion
coefficient( ADC) values of cervical cancer，and discuss the application value of T2WI and DWI in the
diagnosis of cervical cancer and the effect of radiotherapy for patients with cervical cancer．Methods: 50
cases of cervical cancer were selected from 2014－01～2015－06 in the Affiliated Hospital of Inner Mongolia
Medical University，all patients were treated with MR sagittal T2WI fat suppression sequence and
ADC scan ( b = 1000 s /mm² ) ，the magnetic resonance imaging findings of cervical cancer were
analyzed， the imaging findings of cervical cancer before and after radiotherapy were observed，measuring
the ADC values and the difference was compared before and after radiotherapy．Results: 48 cases of cervical
cancer patients in the sagittal T2WI fat suppression sequence displayed different degrees of violation
on the uterine muscle layer， the film layer， the vagina，only 2 cases no obvious abnormalities in the
conventional MR sagittal T2WI．50 cases of cervical cancer patients had varying degrees of high signal
on DWI．After radiotherapy， 24 patients were significantly reduced or even disappeared， the ADC value
of the lesion area was significantly higher than that before radiotherapy，and the ratio of the two patients
was statistically different．20 patients with pathological changes part residual，6 cases of recurrence after
radiotherapy， the ADC values before radiotherapy had no significant statistical difference，but with the
ADC values returned to normal or inflammatory reaction after radiotherapy group was significant statistical
different．Conclusion: Combing T2WI with DWI technique is an effective and practical method to
diagnose cervical cancer and evaluate the effects of cervical cancer patients after radiotherapy．

R737．33; R 445．2

 收稿日期: 2016－01－11; 修回日期: 2016－04－04
基金项目: 内蒙古自治区卫生厅项目( 2013MS1196)
作者简介: 白雪菲( 1989－) 女，内蒙古医科大学附属医院核磁共振室医师，医学硕士。
通讯作者: 郭冬玲，主任技师，E－mail: 1633316799@ qq．com 内蒙古医科大学附属医院核磁共振室， 010050