目的:探讨冠心病介入治疗后cTn － T 的变化，分析cTn － T 升高的相关因素及对病人临床预后的影
响。方法:选择在我院成功行PCI 手术的60 例冠心病病人，测定PCI 前、后24 hcTn － T 水平，并详细记录临床资
料及PCI 术中的相关操作因素，按照术后cTn － T 升高与否，分为升高组(21 例) 和正常组(39 例)。比较两组间
冠脉病变支数及手术相关操作因素的差别。并进行院内随访，观察病人临床结局。结果:冠心病病人介入治疗
后cTn － T 升高率为35%，cTn － T 升高组和cTn － T 正常组在年龄、性别、体重指数、吸烟史、高血压史、糖尿病
史、高血脂、病变血管支数方面的差别无统计学意义(P 值＞ 0． 05)。在支架释放及血管扩张时压力总合、球囊扩
张时间总和、球囊扩张次数、支架长度、支架直径及支架数目方面的差别有统计学意义(P 值＜ 0． 05)。cTn － T
升高组较cTn － T 正常组，心纹痛症状发生者较多，且cTn － T 升高组病人住院时间明显延长。结论:PCI 术可引
起心肌损伤，且与支架释放及血管扩张压力总合、球囊扩张时间总和、球囊扩张次数、支架数目、支架长度、支架
直径有关。并能在一定程度上决定病人的预后

Objective:To observe the change of cardiac troponin － T( cTn － T) after percutaneous
coronary intervention(PCI)． The factors with related to intervention procedures to patients with cTn － T
elevation after PCI and the impact of the risk of cTn － T on the clinical outcomes were investigated．
Methods:60 patients were chosen after successful PCI in our hospital． cTn － T levels were measured
before and at 24 h after the procedure，the clinical characteristics of patients and factors with related to
intervention procedures were recorded． The patients with normal cTn － T before PCI were classified into
groupⅠ(cTn － T positive，21 cases) and group Ⅱ( cTn － T negative，39 cases) by levels of cTn － T
post intervention． Comparison about the number of lesion vessels and the relative factors in PCI were
performed between two groups． The clinical outcomes of the patients were follow － up． Results:The positive
rate of cTn － T was 35%after PCI． The differences in sex、age、BMI、history of smoking，、hypertension，
、diabetes mellitus、hyperlipidemia and the number of lesion vessels were no statistical significance
between every two groups(P ＞ 0． 05)． There were statistical differences in inflation pressure、total time
of inflation、dilated times、length and diameter of stent and the number of stents between groupⅠand
group Ⅱ(P ＜ 0． 05)． The angina onsets were more common and the length of stay were longer in the
patients with the rise of cTn － T than those without． Conclusion:PCI may cause myocardial injury，
which is associated to inflation pressure、total time of inflation、dilated times，length and diameter
of stent and the number of stents． To a certain extent the level of troponin Can predict the outcomes．

R541． 4